Answered step-by-stepDrug Drug Class Mechanism of Action Adv

Answered step-by-stepDrug Drug Class Mechanism of Action Adverse Effects Nursing…Drug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsNaloxone HydrochlorideNaltrexone (ReVia) ____1___ ____2_______ Anxiety, irritability, chills, hot flashes, rhinorrhea, diarrhea, confusion, abdominal cramps, nausea vomiting   Use with caution in patients with cardiac disease – Monitor for cardiac arrythmias. ****After the nurse had administered to a patient to reverse opioid effect, what should they look for ____3_____   Gabapentin, Venlafaxine, Bupivacaine, Baclofen, Cyclobenzaprine, Ketamine, Duloxetine, Nortriptyline ___4_____ Activate innate immune responses to produce a local immuno-competent environment at the injection site.  respiratory depression, sedation, constipationurinary retentionnausea   Depending upon the medication used. **Aspirin, Diclofenac, Ibuprofen, Ketoprofen, Ketorolac, Meloxicam, Naproxen, Celecoxib Non-Opioid analgesics NSAIDS-Inhibits COX-1 and COX-2, inhibits prostaglandins. ASA- causes irreversible inhibition of COX (different from NSAIDs) GI distressPeptic Ulcer diseaseKidney and liver impairmentTarry stools Blood dyscrasias: thrombocytopenia, leukopenia, neutropenia, hemolytic anemias Bone marrow depression and impaired coagulation  Monitor (labs): __5___ & __6___(hint: look at Adverse effects) Teach Patient: Take with meals or milk to reduce GI irritationAvoid drinking alcohol, smoking and aspirin when taking other NSAIDs MorphineFentanylHydromorphone Codeine SulfateMeperidine (do not use in elderly)Methadone ____7___ ___8_____ 1. ___9_____*2. ___10____*3. ____11___*4.Cough suppression5. Itching6. Pupil Constriction7. Diaphoresis and flushing Antidote: ___12________ 1. Monitor vital signs (_13_ & _14__)2. Teach patient to rise slowly.3. Monitor for constipation Administered: IV, Transdermal, Transmucosal, Nasal Spray, PO, Sublingual spray  Antidote: 15. ______ (opioid antagonist)      “Morphine is the opioid of choice for decreasing pain from myocardial  infarction. ” Drug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsAcetaminophen 16. ____ and 17.   ___ (not anti-inflammatory) Inhibits prostaglandin synthesis Can cause       18___ (which main organ) damageDark urinerashClay colored stools Antidote: 19. ____ Monitor: 20. _______Teach: Careful when taking with other medications that already contains             21. ____ (i.e., Percocet)Buprenorphine (used to treat opioid addiction)  Agonist-antagonist   Indicated for: Used an         22. ___ and to treat              23. _____ addiction   HeadacheDrowsinessNausea, vomitingIncreased sweatingInability to sleep Avoid driving or drinking when taking this medication. Do not take with other narcotics   Pentazocine (nalbuphine, butorphanol  Agonist-antagonist    Antagonist: Acts on opioid receptor sites Agonist: produces an antagonistic effect when given to patients taking opioids  Respiratory depression**Nausea, vomiting diarrhea 24. _____* Tachycardia 25. _____  Monitor vitals especially: (hint adverse reaction column) ___26__and ___27___  Naloxone (Narcan) ___28__ Blocks and reverses effects. Binds to receptors in the brain _29__ _30___   Administration: IV, intranasal, IM, subQ*if administered before opioid -blocks effects, if administered after opioid, it will reverse the effects of drug         Adjuvant MedicationsDrug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsLidocaine (Lidoderm) Topical analgesic  Local anesthetic used to relieve neuropathic pain (postherpetic neuralgia) Redness or irritation to skinDizzinessConfusionCautioned in patients who are taking Class I antiarrhythmic drugs Treat: neuralgia due to herpetic Wash hands after handlingApply to area that is painful.  Gabapentin (Neurontin) Treats: Neuropathic Pain Antiseizure 31._______ DrowsinessDizzinessTirednessTremors  Indication (Used to Treat) 32. _______1. Teach patient medication is used to alleviate pain and not for the Rx’s original purpose.  Pregabalin (Lyrica) Indicated for:  neuropathic  pain   associated  with  diabetic   neuropathy, postherpetic neuralgia Antiseizure/Antidepressant    binds to calcium channels and decreases the inflow of calcium at nerve endings. dizziness*Somnolence* which often  persist  as   long  as  the   drug  is  being   taken.3. Blurred vision may  develop  during   early  therapy,  but   resolves  with  continued drug use” Pregabalin (33)does/does not  interact with oral contraceptive. Does not alter any antiseizure drugs studied (carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproic acid, and tiagabine)”             GlucocorticoidsDrug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsPrednisonePrednisolone Glucocorticoids Decrease Inflammation Short term: Weight gain, hyperglycemia Long term: bone loss, adrenal suppression, exogenous glucocorticoid- Cushing Syndrome Monitor:  __34___ in clients with diabetes Methotrexate     Other DMARDS HydroxychloroquineLeflunomideSulfasalazine Non-biologic DMARDS Slows disease progress and decreased joint destruction  (Methotrexate Only)Contraindicated in pregnancy.Can cause fetal death and congenital abnormalities. Blackbox Warning (Methotrexate): ______36_______ (Methotrexate Only)Should be taken with __35___(vitamin?) to reduce GI and hepatic toxicity.  Teach: Patient should receive annual influenza. Avoid people who are sick and perform frequent handwashing                   Drug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsNaloxone HydrochlorideNaltrexone (ReVia) ____1___ ____2_______ Anxiety, irritability, chills, hot flashes, rhinorrhea, diarrhea, confusion, abdominal cramps, nausea vomiting   Use with caution in patients with cardiac disease – Monitor for cardiac arrythmias. ****After the nurse had administered to a patient to reverse opioid effect, what should they look for ____3_____   Gabapentin, Venlafaxine, Bupivacaine, Baclofen, Cyclobenzaprine, Ketamine, Duloxetine, Nortriptyline ___4_____ Activate innate immune responses to form a local immuno-competent environment at the injection site.  respiratory depression, sedation, constipationurinary retentionnausea   Depending upon the medication used. **Aspirin, Diclofenac, Ibuprofen, Ketoprofen, Ketorolac, Meloxicam, Naproxen, Celecoxib Non-Opioid analgesics NSAIDS-Inhibits COX-1 and COX-2, inhibits prostaglandins. ASA- causes irreversible inhibition of COX (different from NSAIDs) GI distressPeptic Ulcer diseaseKidney and liver impairmentTarry stools Blood dyscrasias: thrombocytopenia, leukopenia, neutropenia, hemolytic anemias Bone marrow depression and impaired coagulation  Monitor (labs): __5___ & __6___(hint: look at Adverse effects) Teach Patient: Take with meals or milk to reduce GI irritationAvoid drinking alcohol, smoking and aspirin when taking other NSAIDs MorphineFentanylHydromorphone Codeine SulfateMeperidine (do not use in elderly)Methadone ____7___ ___8_____ 1. ___9_____*2. ___10____*3. ____11___*4.Cough suppression5. Itching6. Pupil Constriction7. Diaphoresis and flushing Antidote: ___12________ 1. Monitor vital signs (_13_ & _14__)2. Teach patient to rise slowly.3. Monitor for constipation Administered: IV, Transdermal, Transmucosal, Nasal Spray, PO, Sublingual spray  Antidote: 15. ______ (opioid antagonist)  “Morphine is the opioid of choice for decreasing pain from myocardial  infarction. ” Drug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsAcetaminophen 16. ____ and 17.   ___ (not anti-inflammatory) Inhibits prostaglandin synthesis Can cause       18___ (which main organ) damageDark urinerashClay colored stools Antidote: 19. ____ Monitor: 20. _______Teach: Careful when taking with other medications that already contains             21. ____ (i.e., Percocet)Buprenorphine (used to treat opioid addiction)  Agonist-antagonist   Indicated for: Used an         22. ___ and to treat              23. _____ addiction   HeadacheDrowsinessNausea, vomitingIncreased sweatingInability to sleep Avoid driving or drinking when taking this medication. Do not take with other narcotics   Pentazocine (nalbuphine, butorphanol  Agonist-antagonist    Antagonist: Acts on opioid receptor sites Agonist: produces an antagonistic effect when given to patients taking opioids  Respiratory depression**Nausea, vomiting diarrhea 24. _____* Tachycardia 25. _____  Monitor vitals especially: (hint adverse reaction column) ___26__and ___27___  Naloxone (Narcan) ___28__ Blocks and reverses effects. Binds to receptors in the brain _29__ _30___   Administration: IV, intranasal, IM, subQ*if administered before opioid -blocks effects, if administered after opioid, it will reverse the effects of drug         Adjuvant MedicationsDrug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsLidocaine (Lidoderm) Topical analgesic  Local anesthetic used to relieve neuropathic pain (postherpetic neuralgia) Redness or irritation to skinDizzinessConfusionCautioned in patients who are taking Class I antiarrhythmic drugs Treat: neuralgia due to herpetic Wash hands after handlingApply to area that is painful.  Gabapentin (Neurontin) Treats: Neuropathic Pain Antiseizure 31._______ DrowsinessDizzinessTirednessTremors  Indication (Used to Treat) 32. _______1. Teach patient medication is used to alleviate pain and not for the Rx’s original purpose.  Pregabalin (Lyrica) Indicated for:  neuropathic  pain   associated  with  diabetic   neuropathy, postherpetic neuralgia Antiseizure/Antidepressant    binds to calcium channels and decreases the inflow of calcium at nerve endings. dizziness*Somnolence* which often  persist  as   long  as  the   drug  is  being   taken.3. Blurred vision may  develop  during   early  therapy,  but   resolves  with  continued drug use” Pregabalin (33)does/does not  interact with oral contraceptive. Does not alter any antiseizure drugs studied (carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproic acid, and tiagabine)”             GlucocorticoidsDrug Drug Class Mechanism of Action Adverse Effects Nursing ImplicationsPrednisonePrednisolone Glucocorticoids Decrease Inflammation Short term: Weight gain, hyperglycemia Long term: bone loss, adrenal suppression, exogenous glucocorticoid- Cushing Syndrome Monitor:  __34___ in clients with diabetes Methotrexate     Other DMARDS HydroxychloroquineLeflunomideSulfasalazine Non-biologic DMARDS Slows disease progress and decreased joint destruction  (Methotrexate Only)Contraindicated in pregnancy.Can cause fetal death and congenital abnormalities. Blackbox Warning (Methotrexate): ______36_______ (Methotrexate Only)Should be taken with __35___(vitamin?) to reduce GI and hepatic toxicity.  Teach: Patient should receive annual influenza. Avoid people who are sick and perform frequent handwashing                                                                                                 24.        Health ScienceScienceNursingNSG 220Share

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