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UMUC Biology 102/103
Lab 5: Meiosis
INSTRUCTIONS:
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On your own and without assistance, complete this Lab 5 Answer Sheet electronically and
submit it via the Assignments Folder by the date listed in the Course Schedule (under
Syllabus).
To conduct your laboratory exercises, use the Laboratory Manual located under Course
Content. Read the introduction and the directions for each exercise/experiment carefully
before completing the exercises/experiments and answering the questions.
Save your Lab 5 Answer Sheet in the following format: LastName_Lab5 (e.g.,
Smith_Lab5).
You should submit your document as a Word (.doc or .docx) or Rich Text Format (.rtf) file
for best compatibility.
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Pre-Lab Questions
1. Compare and contrast mitosis and meiosis.
2. What major event occurs during interphase?
Experiment 1: Following Chromosomal DNA Movement
through Meiosis
Data Tables and Post-Lab Assessment
Trial 1 – Meiotic Division Without Crossing Over Beads Diagram:
Take pictures of your beads for each phase of meiosis I and II without crossing
over. Include notes with your name, date and meiotic stage on index cards in the
pictures. Insert pictures here:
Prophase I
Metaphase I
Anaphase I
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Telophase I
Prophase II
Metaphase II
Anaphase II
Telophase I
Cytokinesis
Trial 2 – Meiotic Division Beads Diagram:
Take a picture of your results for Trial one. Include a note with your name and date
and meiotic stage on an index card in the picture. Insert pictures here:
Prophase I
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Metaphase I
Anaphase I
Telophase I
Prophase II
Metaphase II
Anaphase II
Telophase I
Cytokinesis
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Post-Lab Questions
1. What is the ploidy of the DNA at the end of meiosis I? What about at the end of meiosis II?
2. How are meiosis I and meiosis II different?
3. Why do you use non-sister chromatids to demonstrate crossing over?
4. What combinations of alleles could result from a crossover between BD and bd
chromosomes?
5. How many chromosomes were present when meiosis I started?
6. How many nuclei are present at the end of meiosis II? How many chromosomes are in each?
7. Identify two ways that meiosis contributes to genetic recombination.
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8. Why is it necessary to reduce the number of chromosomes in gametes, but not in other cells?
9. Blue whales have 44 chromosomes in every cell. Determine how many chromosomes you
would expect to find in the following:
i. Sperm Cell:
ii. Egg Cell:
iii. Daughter Cell from Mitosis:
iv. Daughter Cell from Meiosis II:
10. Research and find a disease that is caused by chromosomal mutations. When does the
mutation occur? What chromosomes are affected? What are the consequences?
11. Diagram what would happen if sexual reproduction took place for four generations using
diploid (2n) cells.
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Experiment 2: The Importance of Cell Cycle Control
Data Tables and Post-Lab Assessment
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Post-Lab Questions
1. Record your hypothesis from Step 1 in the Procedure section here.
2. What do your results indicate about cell cycle control?
3. Suppose a person developed a mutation in a somatic cell which diminishes the performance
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of the body’s natural cell cycle control proteins. This mutation resulted in cancer, but was
effectively treated with a cocktail of cancer-fighting techniques. Is it possible for this person’s
future children to inherit this cancer-causing mutation? Be specific when you explain why or
why not.
4. Why do cells which lack cell cycle control exhibit karyotypes which look physically different
than cells with normal cell cycle.
5. What are HeLa cells? Why are HeLa cells appropriate for this experiment?
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